There are 18 disease interactions with Calcidrine (anhydrous calcium iodide / codeine) which include: impaired GI motility Anesthesiology 81 Large doses and/or rapid intravenous administration may produce bradycardia and arrhythmia via stimulation of medullary vagal nuclei. J Pharmacol Exp Ther 199 The relevance of a particular drug interaction to a specific individual is difficult to determine. With repeated injections, an excessive amount may be absorbed suddenly if normal circulation is reestablished. (1975): 835, Zsigmond EK, Vieira ZEG, Duarte B, Renigers SA, Hirota K "Double-blind placebo-controlled ultrasonographic confirmation of constriction of the common bile duct by morphine." We comply with the HONcode standard for trustworthy health information -, Search the entire Drugs.com site for anhydrous calcium iodide. Anesth Analg 81 14th ed." The use of narcotic (opioid) analgesic agents is contraindicated in premature infants. Orlaam (levomethadyl acetate)" Roxanne Laboratories Inc, Columbus, OH. Anesth Analg 65 Addiction-prone individuals, such as those with a history of alcohol or substance abuse, should be under careful surveillance or medical supervision when treated with opiate agonists. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. JAMA 196 Major Potential Hazard, Moderate plausibility. Clin Pharm 5 Br J Anaesth 56 Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. The effects on smooth muscle tone appear to be the most pronounced with morphine. Applies to: Altered Consciousness, Asphyxia, Brain/Intracranial Tumor, Cerebral Vascular Disorder, Head Injury, Pulmonary Impairment, Respiratory Arrest. "Ventilatory effects of subarachnoid fentanyl in the elderly." It generally occurs as a hydrated compound. Anesthesiology 75 (1982): 1020-1, Stone PA, Macintyre PE, Jarvis DA "Norpethidine toxicity and patient controlled analgesia." Anesth Analg 65 Lancet 06/30/84 (1996): 287, Rigg JR, Ilsley AH, Vedig AE "Relationship of ventilatory depression to steady-state blood pethidine concentrations." Applies to: Liver Disease. Narcotic analgesics (Includes anhydrous calcium iodide/codeine) ↔ impaired GI motility. (1989): 463-9, Gram LF, Schou J, Way WL, et al "delta-Propoxyphene kinetics after single oral and intravenous doses in man." "Product Information. Am Fam Physician 32 Br J Clin Pharmacol 32 Subsequent doses should be titrated based on individual response rather than a fixed dosing schedule. New York, NY: McGraw-Hill Health Professionals Division Anesthesiology 62 (1994): 1211-3, Sebel PS, Bovill JG, Boekhorst RA, Rog N "Cardiovascular effects of high-dose fentanyl anaesthesia." Opiate analgesics cause vasodilatation that may exacerbate hypotension and hypoperfusion and, therefore, are contraindicated in circulatory shock. Gastrointest Endosc 38 NACRES NA.23 JAMA 232 Apnea may result from decreased respiratory drive as well as increased airway resistance, and rigidity of respiratory muscles may occur during rapid IV administration or when these agents are used in the induction of anesthesia. (1977): 433-4, Baselt RC, Casarett LJ "Urinary excretion of methadone in man." It may be prudent to refrain from dispensing large quantities of medication to these patients. Moderate Potential Hazard, Moderate plausibility. Dalgan (dezocine)." Calcium iodates are inorganic compound composed of calcium and iodate anion. Endo Laboratories, Texarkana, TX. Purdue Frederick Company, Norwalk, CT. "Product Information. Surg Gynecol Obstet 177 Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (1985): 205, Kaiko RF, Foley KM, Grabinski PY, et al "Central nervous system excitatory effects of meperidine in cancer patients." "Product Information. These classifications are only a guideline. J Pharm Pharmacol 20 Lilly, Eli and Company, Indianapolis, IN. Available for Android and iOS devices. Anaesthesia 49 "Product Information. Anesthesiology 67 (1988): 353-7, Aitkenhead AR, Vater M, Achola K, Cooper CM, Smith G "Pharmacokinetics of single-dose i.v. "Product Information. J Pharm Pharmacol 24 MS Contin (morphine)." (1991): 1-23, Dershwitz M, Randel GI, Rosow CE, Fragen RJ, Connors PM, Librojo ES, Shaw DL, Peng AW, Jamerson BD "Initial clinical experience with remifentanil, a new opioid metabolized by esterases." Clinical monitoring of pulmonary function is recommended, and equipment for resuscitation should be immediately available if parenteral or neuraxial routes are used. (1978): 488-93, Yue QY, Hasselstrom J, Svensson JO, Sawe J "Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine." (1976): 464-8, Covington EC, Gonsalves-Ebrahim L, Currie KO, et al "Severe respiratory depression from patient-controlled analgesia in renal failure." "Product Information. There are 395 drug interactions with anhydrous calcium iodide / isoproterenol. Drug class (es): expectorants. (1980): 1213-4, Azorlosa JL, Stitzer ML, Greenwald MK "Opioid physical dependence development - effects of single versus repeated morphine pretreatments and of subjects opioid exposure history." Psychopharmacology (Berl) 114 (1980): 665-70, Sjogren P, Dragsted L, Christensen CB "Myoclonic spasms during treatment with high doses of intravenous morphine in renal failure." Available for Android and iOS devices. Obstet Gynecol 39 Br J Anaesth 54 Expert Review Panel". Narcotic (opioid) analgesic agents increase smooth muscle tone in the gastrointestinal tract and decrease peristalsis, which can lead to elevated intraluminal pressure, … "Product Information. Major Potential Hazard, High plausibility. Ann Pharmacother 27 Therapy with opioids should be administered cautiously in patients with gastrointestinal obstruction, constipation, inflammatory bowel disease, or recent gastrointestinal tract surgery. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Calcium iodide (chemical formula CaI2) is the ionic compound of calcium and iodine. (1990): 12-9, Cone EJ, Darwin WD, Gorodetzky CW "Comparative metabolism of codeine in man, rat, dog, guinea-pig and rabbit: identification of four new metabolites." These agents decrease gastrointestinal motility, which may delay the excretion of infective gastroenteric organisms and/or their toxins. J Clin Pharmacol 27 Narcotic (opioid) analgesic agents may prolong and/or worsen diarrhea associated with organisms that invade the intestinal mucosa, such as toxigenic E. coli, Salmonella, Shigella, and pseudomembranous colitis due to broad-spectrum antibiotics.

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